The first set took place during an unrelenting rain storm. Fish teased The Wedge in Cities. Sleeping Monkey was dedicated by Page to people affected by Hurricane Sandy and contained an alternate lyric by Fish: "my sleeping monkey is redeemed."

Alumni Blues was preceded by a Dave's Energy Guide tease. Head Held High was played for the first time since October 31, 1998 (358 shows). The Man Who Stepped Into Yesterday and Avenu Malkenu were played for the first time since June 21, 2009 (136 shows). Bittersweet Motel was played for the first time since August 2, 2009 (132 shows). Purple Rain was played for the first time since July 25, 1999 (316 shows) and included alternate lyrics "tucking in the Purple Rain" and "I am Friar Tuck!" The setbreak featured All-American themed music. Sleeping Monkey contained alternate lyrics "Why'd you tuck my monkey on a train."

Skin It Back was played for the first time since July 29,1988 (1,424 shows). Spanish Moon was teased before and during Skin It Back. Happiness is a Warm Gun was played for the first time since October 31, 1994 (661 shows). Possum and Chalk Dust Torture contained Skin It Back teases. Sand contained an Izabella tease. Before Bug, Trey said the band doesn't speak in words back stage anymore and they decided they only used hand signals. Trey slapped his wrist as if he was being bitten by a bug to indicate Bug. Fluffhead contained a Dave's Energy Guide tease.

The Marco Esquandolas lyric in Antelope was changed to Mike-O Esquandolas, and was followed by a short bass solo by Mike. Light contained a tease of Seven Below from Fish. The soundcheck began with You Can Get It If You Really Want (Jimmy Cliff), which included quotes from Trey of You Can't Always Get What You Want.  Rock On (David Essex) was briefly played after Hey Joe.

Portions of Wilson were performed by Trey on a toy guitar during which Fish teased the beginning drumbeats of Rock and Roll (Led Zeppelin). Reba did not have the whistling ending.

During I Didn’t Know, Trey introduced Fish as “Little Junior Moses Brown Heaps DeWitt” and commented that he was going to “suck all of the moisture out of the air.” During Ya Mar, Page teased It’s Raining, It’s Pouring. Trey teased Flat Fee prior to Disease, which was unfinished. Twist featured an Oye Como Va jam. This show marked the debut of Twenty Years Later.

Drowned featured After Midnight and Jumpin’ Jack Flash teases. Meatstick was played in a different key than normal.

Stealing Time From the Faulty Plan and Kill Devil Falls both debuted at this show, with the latter, remarkably, being played by request. This show featured the first If I Could since June 28, 2000 (103 shows).